Aspergillus flavus secondary metabolic gene clusters

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Syntenic conservation of secondary metabolite gene clusters

  1. Gene clusters identified by Doug Brown
  2. Syntenic comparison done with SynMap: http://genomevolution.org/CoGe/SynMap.pl?dsgid1=8171;dsgid2=7146;c=4;D=20;g=10;A=5;Dm=;gm=;w=0;b=1;ft1=1;ft2=1;do1=1;do2=1;do=40;dt=geneorder
  3. Merging of data by custom perl script.

Gene cluster 48

###cluster_48
AFLA_121440     AO070319000038  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880786;fid2=58351035;dsgid1=7146;dsgid2=8171
AFLA_121450     AO070319000037  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880789;fid2=58351040;dsgid1=7146;dsgid2=8171
AFLA_121460     No syntenic gene pair found
AFLA_121470     No syntenic gene pair found
AFLA_121480     No syntenic gene pair found
AFLA_121490     No syntenic gene pair found
AFLA_121500     No syntenic gene pair found
AFLA_121510     No syntenic gene pair found
AFLA_121520     No syntenic gene pair found
AFLA_121530     No syntenic gene pair found
AFLA_121540     No syntenic gene pair found
AFLA_121550     AO070319000034  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880819;fid2=58351062;dsgid1=7146;dsgid2=8171
AFLA_121560     AO070319000033  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880822;fid2=58351065;dsgid1=7146;dsgid2=8171
AFLA_121570     AO070319000031  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880825;fid2=58351069;dsgid1=7146;dsgid2=8171
AFLA_121580     AO070319000030  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880828;fid2=58351073;dsgid1=7146;dsgid2=8171
AFLA_121590     AO070319000029  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880831;fid2=58351078;dsgid1=7146;dsgid2=8171
AFLA_121600     AO070319000028  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880834;fid2=58351082;dsgid1=7146;dsgid2=8171
AFLA_121610     AO070319000027  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880837;fid2=58351086;dsgid1=7146;dsgid2=8171
AFLA_121620     AO070319000026  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880840;fid2=58351093;dsgid1=7146;dsgid2=8171
AFLA_121630     AO070319000025  http://genomevolution.org/CoGe/GEvo.pl?fid1=44880843;fid2=58351096;dsgid1=7146;dsgid2=8171
GEvo comparison of syntenic region between Aspergillus flavus and Aspergillus oryzae at gene cluster 48. Note the identified missing genes between the two strains are not present, though other genes are. Evidence for rapidly evolving gene clusters in terms of gene content.

Add a custom genome of Metabolic gene clusters from Aspergillus flavus

Genome available at OrganismView: http://genomevolution.org/CoGe/OrganismView.pl?dsgid=9105

Syntenic dotplot of Aspergillus flavus versus a minimized genome consisting of only genomic regions containing metabolic gene clusters. Axis coordinates in nucleotides. Analysis can be regenerated at http://genomevolution.org/CoGe/SynMap.pl?dsgid1=7146;dsgid2=9105;c=4;D=20;g=10;A=5;Dm=0;gm=0;w=0;b=1;ft1=1;ft2=1;do1=1;do2=1;do=40;dt=geneorder
Syntenic dotplot of Aspergillus flavus versus a minimized genome consisting of only genomic regions containing metabolic gene clusters. Axis coordinates in nucleotides. Analysis can be regenerated at Syntenic dotplot of Aspergillus flavus versus a minimized genome consisting of only genomic regions containing metabolic gene clusters. Axis metrics in gene units (not nucleotides). Analysis can be regenerated at: http://genomevolution.org/CoGe/SynMap.pl?dsgid1=7146;dsgid2=9105;c=4;D=20;g=10;A=5;Dm=0;gm=0;w=0;b=1;ft1=1;ft2=1;do1=1;do2=1;do=40;dt=geneorder;am=g