In-Paralog: Difference between revisions
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[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]] | [[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]] | ||
In-paralogous genes are essentially [[paralogous]] genes. The nomenclature helps in distinguishing different classes of genes derived from the divergence of lineages (aka events leading to speciation) and the duplication within a lineage when multiple taxa are compared. Specifically, in helps identify cases where two lineages share a gene duplication, but each lineage loses the reciprocal paralog. These genes may be mistakenly be called [[orthologs]] when they are [[out-paralogs]]. | |||
Latest revision as of 22:49, 4 February 2011
In-paralogous genes are essentially paralogous genes. The nomenclature helps in distinguishing different classes of genes derived from the divergence of lineages (aka events leading to speciation) and the duplication within a lineage when multiple taxa are compared. Specifically, in helps identify cases where two lineages share a gene duplication, but each lineage loses the reciprocal paralog. These genes may be mistakenly be called orthologs when they are out-paralogs.