Difference between revisions of "GC content shift"
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Revision as of 16:58, 25 August 2010
GC content shift is an evolutionary genome-wide change in the GC content of an organism. The evolutionary consequences of such a change is unknown. They are detected by comparing the genomes of two related organisms that share a recent common ancestor, and determining if their have different:
- AT/GC genomic composition
- High rate of synonymous mutations for syntenic gene pairs
- Amino acid usage frequencies
- Codon usage frequencies
Comparison of Schizosaccharomyces fungi japonicus strain yFS275 and pombe 972h-
japonicus | pombe | |
---|---|---|
Length | 1 | 10,082,004 |
GC% | 2 | 36 |
AT% | 3 | 64 |
CDS GC% | 4 | 39.5 |
CDS AT% | 5 | 60.5 |
Wobble GC% | 5 | 32.8 |
Wobble AT% | 5 | 67.2 |