Difference between revisions of "In-Paralog"

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[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]]
 
[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]]
  
In-paralogous genes are a special case of homologous genes shared between two species.  These genes are
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In-paralogous genes are essentially [[paralogous]] genes.  The nomenclature helps in distinguishing different classes of genes derived from the divergence of lineages (aka events leading to speciation) and the duplication within a lineage when multiple taxa are compared.  Specifically, in helps identify cases where two lineages share a gene duplication, but each lineage loses the reciprocal paralog.  These genes may be mistakenly be called [[orthologs]] when they are [[out-paralogs]].

Latest revision as of 15:49, 4 February 2011

Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs

In-paralogous genes are essentially paralogous genes. The nomenclature helps in distinguishing different classes of genes derived from the divergence of lineages (aka events leading to speciation) and the duplication within a lineage when multiple taxa are compared. Specifically, in helps identify cases where two lineages share a gene duplication, but each lineage loses the reciprocal paralog. These genes may be mistakenly be called orthologs when they are out-paralogs.