In-Paralog: Difference between revisions
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[[Image:otu.png|frame|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]] | |||
Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can randomly mutate and become identical. This phenomenon is known as gene conversion. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees. | Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can randomly mutate and become identical. This phenomenon is known as gene conversion. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees. | ||
Revision as of 23:53, 21 September 2009
Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can randomly mutate and become identical. This phenomenon is known as gene conversion. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees.