Difference between revisions of "In-Paralog"
From CoGepedia
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[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]] | [[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]] | ||
| − | Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can | + | Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can sometimes undergo a phenomenon known as gene conversion, where one paralog's sequence is converted to another's sequence, making them identical. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees. |
Revision as of 22:01, 22 September 2009
Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can sometimes undergo a phenomenon known as gene conversion, where one paralog's sequence is converted to another's sequence, making them identical. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees.
