Local alignment: Difference between revisions

From CoGepedia
Jump to navigation Jump to search
← Older editNewer edit →
Ambz (talk | contribs)
221 edits
No edit summary
Ambz (talk | contribs)
221 edits
No edit summary
Line 1: Line 1:
Local alignment gives the alignment in which only the most similar regions of ''n'' sequences are aligned in ''n'' dimensions. The measure of similarity will depend on the parameters used for registering a mismatch. The cells of scoring matrix are more homogeneous than those of global alignment matrix. No highest score less than zero is recorded and a pointer is only added when a score is greater than zero. In the end, trace-back begins from the maximum score and ends at the origin of matrix. This variation of assigning scores in a matrix makes local alignment more stringent than global alignment.
Local alignment only aligns the most similar regions between the sequences. The measure of similarity will depend on the parameters used for registering a mismatch. [[Needleman Wunsch]] algorithm is used for local alignment too but with slight variation which makes local alignment more stringent than global alignment.

Revision as of 23:30, 25 September 2009

Local alignment only aligns the most similar regions between the sequences. The measure of similarity will depend on the parameters used for registering a mismatch. Needleman Wunsch algorithm is used for local alignment too but with slight variation which makes local alignment more stringent than global alignment.

Retrieved from "https://genomevolution.org/wiki/index.php?title=Local_alignment&oldid=747"