In-Paralog: Difference between revisions

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[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]]
[[Image:otu.png|thumb|right|500px|Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs]]


Genes arising from gene duplication in given specie without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can sometimes undergo a phenomenon known as gene conversion, where one paralog's sequence is converted to another's sequence, making them identical. Therefore, for two very similar protein sequences in an organism, gene conversion should be taken into account when constructing phylogenomic trees.
Genes arising from gene duplication in a given species without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can sometimes undergo a phenomenon known as gene conversion, where one paralog's sequence is converted by another, making them identical.

Revision as of 00:09, 29 September 2009

Diagram depicting evolutionary relationship between orthologs, in-paralogs and out-paralogs

Genes arising from gene duplication in a given species without any intervening speciation event. Paralogous genes tend to have different functions and contribute to the overall genetic diversity of an organism. However, paralogs can sometimes undergo a phenomenon known as gene conversion, where one paralog's sequence is converted by another, making them identical.