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CoGe can generate basic population genetics summary statistics given a GVCF input file and an annotated genome. | CoGe can generate basic population genetics summary statistics given a GVCF input file and an annotated genome. | ||
= | <style='color:red'>Note: This tool is in Beta Testing. If you use it and have feedback, please email us.</style> | ||
This tool is in Beta Testing. If you use it and have feedback, please email us. | |||
== Summary Statistics == | == Summary Statistics == | ||
These summary statistics are computed per feature overall (gene, CDS, etc) and by 0/4-fold degeneracy (for CDS only): | These summary statistics are computed per feature overall (gene, CDS, etc) and by 0/4-fold degeneracy (for CDS only): | ||
Revision as of 18:08, 4 May 2016
CoGe can generate basic population genetics summary statistics given a GVCF input file and an annotated genome.
<style='color:red'>Note: This tool is in Beta Testing. If you use it and have feedback, please email us.</style>
Summary Statistics
These summary statistics are computed per feature overall (gene, CDS, etc) and by 0/4-fold degeneracy (for CDS only):
- Nucleotide diversity (pi) - average number of pairwise differences between variant sequences
- Watterson's estimator (theta)
- Tajima's D
Steps
1. Load a GVCF file
See the LoadExperiment tool for loading a GCVF file against an existing genome in CoGe.
2. Analyze Diversity
Once the GVCF experiment is loaded, navigate to the experiment view and select "Analyze Diversity".
3. Open the finished result
Open the result in the PopGen tool to see results in tabular and graphical form.
