Global alignment

In the process of global-global alignment, a DNA or a query sequence dictates the length of putative homologs. Based on sequence similarity to query, the top matches are generated by a given algorithm. The entire length of a given match must bear similarity to the entire length of query sequence. Any sequence having partial similarity to query is excluded from the matches. In case of global-local alignment, the word "global" applies to the query and "local" applies to the hit. A given match has only partial similarity to the query such that the entire length of a match aligns partially with query.