SynMap2

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Revision as of 16:42, 20 September 2016 by Asherkhb (Talk | contribs) (Navigating the SynMap2 Viewer)

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Note: This is the documentation for SynMap3D, if you are looking for SynMap2 look here.

Background

SynMap2 is a major reworking of the original SynMap pairwise whole-genome synteny viewer. While the underlying computational framework remains the same, SynMap2 rethinks the visualizations by replacing static images with a high performance and interactive web-based dot-plot viewer. SynMap2’s interactive features allow researchers to explore the dataset from multiple angles in a significantly more intuitive way such as would be expected from the modern web. For example, subsets of syntenic matches can be selected by chromosomal regions or by subset ranges of mutation values (Kn, Ks, or Kn/Ks), and as subsets are selected, the visualization is automatically updated. The subset selection algorithms are designed to work efficiently even when faced with comparisons with many points (such as found in many polyploid species. Another improved feature is auto-persistance based coloring, where an algorithm can determine the most significant peaks at different sensitivity levels and apply unique colors to each, thus allowing researchers to visually distinguish between major duplication events.

Navigating the SynMap2 Viewer

Figure 2. SynMap3D interface.

Navigating the Dotplot

Navigating the Histogram

Other Options

Example Analyses

Species 1 Species 2 Link
H. sapiens (human) P. troglodytes (chimpanzee) https://genomevolution.org/r/lg3o
H. sapiens (human) C. familiaris (dog) https://genomevolution.org/r/lknl
H. sapiens (human) M. musculus (mouse) https://genomevolution.org/r/lknm
A. thaliana B. rapa https://genomevolution.org/r/lknt
Z. mays (maize;corn) S. bicolor (sorghum) https://genomevolution.org/r/lknv
O. niloticus (Nile tilapia) S. salar (Atlantic salmon) https://genomevolution.org/r/lkoj
E. coli (MG1655) E. coli (DH10B) https://genomevolution.org/r/lkng

FAQ