Non-X-alignments: Difference between revisions

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This tracks examples of bacteria and archaea [[syntenic dotplots]] which do not show the classical [[x-alignment]] pattern of inversions.
This tracks examples of bacteria and archaea [[syntenic dotplots]] which do not show the classical [[x-alignment]] pattern of inversions.  One possible methodological reason for these non-x-alignments is mis-assembly.


[[Image:7603 8665.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords.1-1.w800.ct inv.png|thumb|right|500px|Syntenic dotplot generated by SynMap between two species of Methanocaldococcus: Methanocaldococcus fervens strain AG86 (x-axis); Methanocaldococcus sp. strain FS406-22 (y-axis). Results can be regenerated at: http://genomevolution.org/r/oro]]
==Genome-wide random orientation==
[[Image:7603 8665.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords.1-1.w800.ct inv.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two species of Methanocaldococcus: Methanocaldococcus fervens strain AG86 (x-axis); Methanocaldococcus sp. strain FS406-22 (y-axis). Results can be regenerated at: http://genomevolution.org/r/oro]]
 
[[Image:Master 6989 3415.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords ctinv.w500.37423447.33394801.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two species of Thermococcus: gammatolerans strain DSM 15229; EJ3 (x-axis); onnurineus strain NA1 (y-axis). Results can be regenerated at: http://genomevolution.org/r/os7]]
 
==Local region of syntenic instability==
These are interesting.  Lots of inversions at the same local sub-regions, but not around a single point in the genome.  Multiple events appear to be independent by comparison to different genomes.  Perhaps there is some factor contributing to a local region of syntenic instability?
 
[[Image:Master 6948 6963.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords ctinv.w500.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: M.14.25 (x-axis); Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osn]]
 
[[Image:Master 8988 6963.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords ctinv.w500.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: L.D.8.5 (x-axis); Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/oso]]
 
[[Image:Master 6946 6963.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords ctinv.w500.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: strain L.S.2.15 (x-axis); strain Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osp]]
 
[[Image:6963 3408.CDS-CDS.lastz.dag.go c4 D20 g10 A5.aligncoords.gcoords.1-1.w800.flip.ct inv.png|thumb|center|500px|Syntenic dotplot generated by SynMap between two species of Sulfolobus: solfataricus strain P2 (x-axis); islandicus strain Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osg]]

Latest revision as of 20:42, 21 August 2010

This tracks examples of bacteria and archaea syntenic dotplots which do not show the classical x-alignment pattern of inversions. One possible methodological reason for these non-x-alignments is mis-assembly.

Genome-wide random orientation

Syntenic dotplot generated by SynMap between two species of Methanocaldococcus: Methanocaldococcus fervens strain AG86 (x-axis); Methanocaldococcus sp. strain FS406-22 (y-axis). Results can be regenerated at: http://genomevolution.org/r/oro
Syntenic dotplot generated by SynMap between two species of Thermococcus: gammatolerans strain DSM 15229; EJ3 (x-axis); onnurineus strain NA1 (y-axis). Results can be regenerated at: http://genomevolution.org/r/os7

Local region of syntenic instability

These are interesting. Lots of inversions at the same local sub-regions, but not around a single point in the genome. Multiple events appear to be independent by comparison to different genomes. Perhaps there is some factor contributing to a local region of syntenic instability?

Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: M.14.25 (x-axis); Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osn
Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: L.D.8.5 (x-axis); Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/oso
Syntenic dotplot generated by SynMap between two strains of Sulfolobus islandicus: strain L.S.2.15 (x-axis); strain Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osp
Syntenic dotplot generated by SynMap between two species of Sulfolobus: solfataricus strain P2 (x-axis); islandicus strain Y.G.57.14 (y-axis). Results can be regenerated at: http://genomevolution.org/r/osg