X-alignment
(Redirected from X-alignments)
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X-alignments [1] are the result of visualizing sytnenic dotplots between bacterial genomes reflecting the high likelihood of genomic inversions happening symmetrically around the origin of replication. Since most linear representations of bacterial genomes begin at the origin, many such inversion events between two bacterial genomes result in their syntenic dotplot having and "X"-like pattern.
Please see non-X-alignments for exceptions to this (mostly found in Archaea).
- ↑ Eisen,J.A., Heidelberg,J.F., White,O. and Salzberg,S.L. (2000) Evidence for symmetric chromosomal inversions around the replication origin in bacteria. Genome Biol., 1, 1101–1109.