Difference between revisions of "Genomic inversion"
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A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to non-homologous recombination. | A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to non-homologous recombination. | ||
− | ===Bacteria== | + | ===Bacteria=== |
− | In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the [[origin of replication]]. The latter causes a characteristic pattern in syntenic dotplots called an [[x alignment]]. | + | In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the [[origin of replication]]. The latter causes a characteristic pattern in [[syntenic dotplots]] called an [[x alignment]]. |
Revision as of 11:20, 18 February 2010
Definition
A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to non-homologous recombination.
Bacteria
In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the origin of replication. The latter causes a characteristic pattern in syntenic dotplots called an x alignment.