Difference between revisions of "GC content shift"

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(Created page with 'GC content shift is an evolutionary genome-wide change in the GC content of an organism. The evolutionary consequences of such a change is unknown. They are detected by compari...')
 
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*Amino acid usage frequencies
 
*Amino acid usage frequencies
 
*Codon usage frequencies
 
*Codon usage frequencies
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==Comparison of Schizosaccharomyces fungi japonicus strain yFS275 and pombe 972h-==
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[[Image:GEvo-Schizosaccharomyces.png|thumb|right|500px|GEvo analysis of syntenic regions from the Schizosaccharomyces fungi japonicus strain yFS275 (top) and pombe 972h- (bottom). Gene models are colored based on the percent GC content of GC3.  Red is AT rich; green GC rich; yellow 50/50 AT/GC.  Results may be regenerated at: http://genomevolution.org/r/pi7]]

Revision as of 16:38, 25 August 2010

GC content shift is an evolutionary genome-wide change in the GC content of an organism. The evolutionary consequences of such a change is unknown. They are detected by comparing the genomes of two related organisms that share a recent common ancestor, and determining if their have different:

  • AT/GC genomic composition
  • High rate of synonymous mutations for syntenic gene pairs
  • Amino acid usage frequencies
  • Codon usage frequencies

Comparison of Schizosaccharomyces fungi japonicus strain yFS275 and pombe 972h-

GEvo analysis of syntenic regions from the Schizosaccharomyces fungi japonicus strain yFS275 (top) and pombe 972h- (bottom). Gene models are colored based on the percent GC content of GC3. Red is AT rich; green GC rich; yellow 50/50 AT/GC. Results may be regenerated at: http://genomevolution.org/r/pi7