Difference between revisions of "Syntenic dotplot"

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Syntenic dotplot between two '''Escherichia coli''' genomes:  B strain REL606 and strain K-12 substrain DH10B.  This dotplot was generated using [[SynMap]] can be regenerated [http://synteny.cnr.berkeley.edu/CoGe/SynMap.pl?dsgid1=7454;dsgid2=4241;D=20;g=10;A=5;w=0;b=1;ft1=1;ft2=1;dt=geneorder;autogo=1 here].
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Syntenic dotplot between two '''Escherichia coli''' genomes:  (x-axis) B strain REL606 and (y-axis) strain K-12 substrain DH10B.  This dotplot was generated using [[SynMap]] can be regenerated [http://synteny.cnr.berkeley.edu/CoGe/SynMap.pl?dsgid1=7454;dsgid2=4241;D=20;g=10;A=5;w=0;b=1;ft1=1;ft2=1;dt=geneorder;autogo=1 here].
  
 
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Revision as of 13:39, 6 October 2009

Dotplot.png

Syntenic dotplot between two Escherichia coli genomes: (x-axis) B strain REL606 and (y-axis) strain K-12 substrain DH10B. This dotplot was generated using SynMap can be regenerated here.

Variation observed in B and K12
Description of variation
Link leading to GEvo
1. Deletion in B strain
DNA pol II, genes in metabolic pathway, thiamine ABC transporter present in K12 strain Transposase in K12 strain. Prophage CP46 DNA insertion in K12 strain.
http://tinyurl.com/yexrzpb
2. Insertions in K12 strain
Transposase in K12 strain. Prophage CP46 DNA insertion in K12 strain.
http://tinyurl.com/yd2quy7
3. Deletion in B strain or Insertion in K12 strain
Presence of lac operon and other metabolic enzymes genes in K12 strain. Pseudogene made by transposon insertion in K12. http://tinyurl.com/yedn5tb
4. Insertion in B strain and DNA duplication event in K12.
Prophage DNA insertion in B strain. Recent DNA duplication event in K12 as seen by 100% identity between paralogs. http://tinyurl.com/yea8bu6
5. Insertion in B strain
Bacteriophage DNA insertion in B strain http://tinyurl.com/yevlb2w
6. Insertion in B strain
Prophage DNA insertion in B strain http://tinyurl.com/ybokuag
7. Insertion in K12 strain
Prophage DNA insertion in K12 http://tinyurl.com/yaxlh7o
8. Insertion of transposon in K12 and B strain. Deletion of phenylacetic acid genes in B strain or insertion of those in K12.
Rac prophage DNA insertion in K12. Insertion of IS3 element protein and transposase in B strain. Insertion of IS30 transposon in B strain created pseudogene. Presence of phenylacetic acid degradation genes in K12 http://tinyurl.com.ye7wcxe
9. Insertion in K12 strains.
Flagella synthesizing genes either deleted in B strain or inserted in K12.

Presence of flagella encoding/regulatory genes in K12. IS5 sequence insertion in K12. CP4-44 prophage DNA insertion in K12. http://tinyurl.com/ybh84x7


10. Insertion in B strain.
Pili associated genes and metal resistance genes either inserted in K12 or deleted in B strain.

Bacteriophage DNA insertion in B strain.
IS1 sequence insertion in B strain.
Presence of pili associated genes in K12 together with genes conferring resistance to Co and Ni.

http://tinyurl.com/yammj7v
11. Insertion in K12 strain. ParB family protein and recombinase deleted in K12.
CP4-57 prophage DNA insertion in K12 strain. Presence of ParB family protein gene and recombinase in B strain
http://tinyurl.com/ycdog2c
12. Insertion in B and K12 strain. Inversion. Insertion of saframycin synthetase in B strain or deletion of that in K12.
Prophage DNA insertion in B strain.
Inversion of prepilin leader peptidase/methylase and M-type protein. Is5 insertion in K12. Presence of saframycin synthetase gene in B strain.


http://tinyurl.com/ycoagxh
13. Insertion of transposon, ShiA-like, TrbC-like proteins in B strain.
IS30 transposon insertion in B strain. Presence of ShiA-like and TrbC-like protein in B strain
http://tinyurl.com/ydkrcv8
14. Insertion in B strain
Insertion of fimbriae synthesis genes, multi drug transporters, Is1 protein gene in B strain.
http://tinyurl.com/ycwsmsl