Difference between revisions of "Popgen"

From CoGepedia
Jump to: navigation, search
m (Summary Statistics)
m (1. Load a GVCF file)
Line 9: Line 9:
 
== Steps ==
 
== Steps ==
 
===1.  Load a GVCF file===
 
===1.  Load a GVCF file===
See the [[LoadExperiment]] tool to load a GCVF file against an existing genome in CoGe.
+
See the [[LoadExperiment]] tool for loading a GCVF file against an existing genome in CoGe.
  
 
===2.  Analyze Diversity===
 
===2.  Analyze Diversity===

Revision as of 11:54, 1 March 2016

CoGe can generate basic population genetics summary statistics given a GVCF input file and an annotated genome.

Summary Statistics

These summary statistics are computed per feature overall (gene, CDS, etc) and by 0/4-fold degeneracy (for CDS only):

  • Nucleotide diversity (pi) - average number of pairwise differences between variant sequences
  • Watterson's estimator (theta)
  • Tajima's D

Steps

1. Load a GVCF file

See the LoadExperiment tool for loading a GCVF file against an existing genome in CoGe.

2. Analyze Diversity

In the resulting experiment's menu select "Analyze Diversity".

Diversity analysis menu option

3. Open the finished result

Open the result in the PopGen tool to see results in tabular and graphical form.

Example table of summary statistics
Example plot of selected summary statistics