Difference between revisions of "SynFind"

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==Options for Synteny Score==
 
==Options for Synteny Score==
* '''Window Size''':    synteny window size [default: 40]
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* '''Window Size''':    synteny window size in genes [default: 40]
* '''Cutoff''':    the minimum number of anchors to call synteny [default: 0.1]
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** The Window Size is the size of the genomic regions compared between two genomes using genes as the metric.  Given an anchor gene, the window size is divided by 2 and that many genes searched up and downstream from the anchor.
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** Example, a window size of 40 means that a total of 41 genes are checked: the anchor gene; plus 20 upstream; plus 20 downstream.
 +
* '''Cutoff''':    the minimum number of anchors to call synteny.  This is a percentage of the total number of genes in a window. [default: 0.1]
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** Valid value range:  (0,1]
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** Example:  Window size of 40; cutoff value of 0.1: 4 gene-pairs must be identified for a region to be called syntenic.
 
* '''Scoring Function''':  scoring scheme, must be one of ('collinear', 'density') [default: collinear]
 
* '''Scoring Function''':  scoring scheme, must be one of ('collinear', 'density') [default: collinear]
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** Collinear:  a collinear arrangement of syntenic genes in enforced
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** Density: any arrangement of gene-pairs is tolerated

Revision as of 18:29, 4 February 2012

Overview

SynFind identified syntenic regions against any set of genomes given a gene in one genome. The primary algorithm of this analysis is SyntenyScore written by Haibao Tang.

Options for Synteny Score

  • Window Size: synteny window size in genes [default: 40]
    • The Window Size is the size of the genomic regions compared between two genomes using genes as the metric. Given an anchor gene, the window size is divided by 2 and that many genes searched up and downstream from the anchor.
    • Example, a window size of 40 means that a total of 41 genes are checked: the anchor gene; plus 20 upstream; plus 20 downstream.
  • Cutoff: the minimum number of anchors to call synteny. This is a percentage of the total number of genes in a window. [default: 0.1]
    • Valid value range: (0,1]
    • Example: Window size of 40; cutoff value of 0.1: 4 gene-pairs must be identified for a region to be called syntenic.
  • Scoring Function: scoring scheme, must be one of ('collinear', 'density') [default: collinear]
    • Collinear: a collinear arrangement of syntenic genes in enforced
    • Density: any arrangement of gene-pairs is tolerated