Difference between revisions of "Genomic inversion"
From CoGepedia
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===Definition=== | ===Definition=== | ||
| − | A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to non-homologous recombination. | + | A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to [[non-homologous recombination]]. |
===Bacteria=== | ===Bacteria=== | ||
In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the [[origin of replication]]. The latter causes a characteristic pattern in [[syntenic dotplots]] called an [[x alignment]]. | In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the [[origin of replication]]. The latter causes a characteristic pattern in [[syntenic dotplots]] called an [[x alignment]]. | ||
Revision as of 11:28, 18 February 2010
Syntenic dotplot generated by SynMap between two strains of Yersinia pseudotuberculosis showing one inversion. Strain IP 31758 (x-axis); strain YPIII (y-axis). Results can be regenerated at: http://synteny.cnr.berkeley.edu/CoGe/SynMap.pl?dsgid1=1911;dsgid2=1906;D=20;g=10;A=5;w=0;b=1;ft1=1;ft2=1;dt=geneorder
GEvo analysis of inversion breakpoints identified in two strains of Yersinia pseudotuberculosis. At the breakpoints are ribosomal gene cassettes (shown as gray and yellow arrows). Results can be regenerated at: http://tinyurl.com/yj38xw6
Definition
A genomic inversion is when a region of a genome or chromosome gets flipped in place. These usually happen at genomic regions with nearly identical sequence, implying a mechanism similar to non-homologous recombination.
Bacteria
In bacterial genomes, inversion often occur at transposon or ribosomal gene sequences, and happen symmetrically around the origin of replication. The latter causes a characteristic pattern in syntenic dotplots called an x alignment.
