Difference between revisions of "Whole-genome shotgun"
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Latest revision as of 18:55, 19 February 2011
One method of preparing a genome for sequencing. The genome to be sequenced is sheared into many small pieces. The ends of this set of small pieces are sequenced (usually by a multiplexed approach). This creates a very large collection of short sequences (~100-1000nt in length). This collection is then assembled into a genome using a variety of approaches: